A1. Widefield / Epi-illumination at Achucarro Basque Center for Neurosciences - Imaging Facility

High Content Screening combines automated fluorescence imaging with quantitative image analysis to enable multiparametric evaluation of cellular phenotypes at scale. This technology supports high-throughput acquisition and extraction of morphological and functional data, facilitating applications such as compound screening, phenotypic profiling, and cellular pathway analysis in complex biological models.

Widefield fluorescence imaging enables rapid acquisition of labeled biological samples across multiple spectral channels, providing versatile visualization of cellular and tissue structures. This approach supports efficient screening and documentation workflows and can be integrated with automated acquisition and environmental control to monitor biological processes over time.